Journal article
Effects of chronic omega-3 polyunsaturated fatty acid supplementation on human atrial electrophysiology
S Kumar, F Sutherland, R Rosso, AW Teh, G Lee, PM Heck, A Feldman, C Medi, S Watt, ML Garg, PB Sparks
Heart Rhythm | Published : 2011
Abstract
Background: Omega-3 polyunsaturated fatty acids in fish oils may have antifibrillatory effects. Their mechanism of action in humans is poorly understood. Objective: The purpose of this study was to investigate the effects of chronic fish oil supplementation on human atrial electrophysiology (EP). Methods: Two groups of patients without clinical AF or structural heart disease and fish intake ≤1/week were prospectively recruited into a control group (n = 30) and a fish oil group (n = 31). The latter were prescribed 6 g/day of fish oil for <1 month before an EP study. The following were compared at time of EP study: serum omega-3 levels; right atrial and coronary sinus effective refractory peri..
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Grants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
This manuscript was presented in part at the Annual Scientific Sessions of the Heart Rhythm Society, May 2010 in Denver, Colorado, USA. This study was funded in part by the National Heart Foundation and the Pfizer Cardiovascular Lipid Research Grant. Dr. Kumar is the recipient of a postgraduate research scholarship cofunded by the National Health and Medical Research Council and the National Heart Foundation of Australia (Scholarship ID 628996). Drs. Teh and Medi are recipients of a postgraduate research scholarship funded by the National Heart Foundation. Dr. Lee is a recipient of the postgraduate research scholarship from the Cardiac Society of Australia and New Zealand.